Clinical Chemistry: Theory, Analysis, Correlation, 4th ed. Lawrence A. Kaplan, Amadeo J. Pesce, and Steven C. Kazmierczak, editors. St. Louis, MO: Mosby, 2003, 1179 pp., $86.95. ISBN 0-323-01716-9 (Book is accompanied by a CD-ROM).

![Graphic][1] Seven years after the appearance of the last edition, the editors of this very well-accepted textbook present the fourth edition in cooperation with 73 contributors. This is one of the first clinical chemistry textbooks published in the current millennium. In their foreword, the editors state that this book, although useful as reference for clinical chemistry professionals, is primarily written for students and instructors of clinical chemistry and laboratory medicine. The text is organized into two large parts, Laboratory Techniques (23 chapters) and Pathophysiology (34 chapters), and is accompanied by a CD-ROM that includes additional information. All of the details regarding methodology now appear only on the accompanying CD, which allowed the number of methods described to increase to more than 115 and the content for each method to be expanded. References on the CD-ROM are now inserted as popups. Also new are ∼300 World Wide Web addresses that the authors believe are worthwhile for investigation; on the CD-ROM these addresses are in hyperlink format. Many of the chapters in the textbook have been … [1]: /embed/inline-graphic-1.gif