1,3-Dicyclohexylcarbodiimide

[538-75-0] C13H22N2 (MW 206.33) InChI = 1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2 InChIKey = QOSSAOTZNIDXMA-UHFFFAOYSA-N (powerful dehydrating agent commonly used for the preparation of amides,2 esters,3 and anhydrides;4 used with DMSO for the mild oxidation of alcohols to ketones;5 used in the dehydrative conversion of primary amides to nitriles,6 β-hydroxy ketones to α,β-unsaturated ketones,7 and can effect the stereochemical inversion of secondary alcohols8) Alternate Name: DCC. Physical Data: mp 34–35 °C; bp 122–124 °C. Solubility: highly sol dichloromethane, THF, acetonitrile, DMF. Form Supplied in: opalescent solid; widely available. Handling, Storage, and Precautions: is an acute skin irritant in susceptible individuals. Because of its low melting point, it is conveniently handled as a liquid by gentle warming of the reagent container. It should be handled with gloves in a fume hood, and stored under anhydrous conditions.