医学
子痫前期
胎盘
产科
置信区间
弹性成像
脐动脉
胎儿
怀孕
内科学
超声波
放射科
遗传学
生物
作者
Fahrettin Kılıç,Yasemin Kayadibi,Mehmet Aytaç Yüksel,İbrahim Adaletli,Fethi Emre Ustabaşıoğlu,Mahmut Öncül,Rıza Madazli,Mehmet Yılmaz,İsmail Mihmanlı,Fatih Kantarcı
出处
期刊:Diagnostic and interventional radiology
[AVES Publishing Co.]
日期:2015-05-08
卷期号:21 (3): 202-207
被引量:88
标识
DOI:10.5152/dir.2014.14338
摘要
We aimed to evaluate the utility of shear wave elastography (SWE) for assessing the placenta in preeclampsia disease.A total of 50 pregnant women in the second or third trimester (23 preeclampsia patients and 27 healthy control subjects) were enrolled in the study. Obstetrical grayscale and Doppler ultrasonography, SWE findings of placenta, and prenatal/postnatal clinical data were analyzed and the best SWE cutoff value which represents the diagnosis of preeclampsia was determined. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of preeclampsia were calculated based on SWE measurements.Mean stiffness values were much higher in preeclamptic placentas in all regions and layers than in normal controls. The most significant difference was observed in the central placental area facing the fetus where the umbilical cord inserts, with a median of 21 kPa (range, 3-71 kPa) for preeclampsia and 4 kPa (range, 1.5-14 kPa) for the control group (P < 0.01). The SWE data showed a moderate correlation with the uterine artery resistivity and pulsatility indices. The cutoff value maximizing the accuracy of diagnosis was 7.35 kPa (area under curve, 0.895; 95% confidence interval, 0.791-0.998); sensitivity, specificity, PPV, NPV, and accuracy were 90%, 86%, 82%, 92%, and 88%, respectively.Stiffness of the placenta is significantly higher in patients with preeclampsia. SWE appears to be an assistive diagnostic technique for placenta evaluation in preeclampsia.
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