医学
乳腺癌
禁忌症
放射治疗
癌症
疾病
乳腺摄影术
老年肿瘤学
临床试验
前瞻性队列研究
内科学
妇科
肿瘤科
替代医学
病理
作者
Nam P. Nguyen,Ulf Karlsson,Eromosele Oboite,Julio Alvarenga,J. Castro Godinez,Alice Zamagni,Micaela Motta,Satya Bose,Vincent Vinh-Hung
出处
期刊:Translational cancer research
[AME Publishing Company]
日期:2020-01-01
卷期号:9 (S1): S228-S235
被引量:2
标识
DOI:10.21037/tcr.2019.10.36
摘要
: The prevalence of breast cancer increases with age. Older breast cancer patients often present with locally advanced disease at presentation because mammography, which diagnosed early stage disease, is not recommended after the age of 75. In addition, they are often undertreated even when they are physically fit and have non-metastatic disease. As a result, survival is often poor. Physicians bias may be a factor in their undertreatment and lack of representation in prospective clinical trials. Physicians should be educated that chronological age is not a contraindication to curative treatment for older breast cancer patients. As a research group devoted to older cancer patients, women, and minorities, the International Geriatric Radiotherapy Group (IGRG) plans to conduct prospective trials to assess biomarkers for frailty, the controversial issue of mammography for older breast cancer patients, and the incorporation of frailty index for curative breast cancer treatment. The data obtained may help to decrease physician bias and to establish future guidelines for older breast cancer patients treatment.
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