Key Renal Neoplasms With a Female Predominance

结节性硬化 病理 嗜酸性 鉴别诊断 肾细胞癌 医学 TFE3型 活检 生物 内科学 生物化学 基因表达 发起人 基因
作者
Nicholas Baniak,Justine A. Barletta,Michelle S. Hirsch
出处
期刊:Advances in Anatomic Pathology [Ovid Technologies (Wolters Kluwer)]
卷期号:28 (4): 228-250 被引量:2
标识
DOI:10.1097/pap.0000000000000301
摘要

Renal neoplasms largely favor male patients; however, there is a growing list of tumors that are more frequently diagnosed in females. These tumors include metanephric adenoma, mixed epithelial and stromal tumor, juxtaglomerular cell tumor, mucinous tubular and spindle cell carcinoma, Xp11.2 ( TFE3 ) translocation-associated renal cell carcinoma, and tuberous sclerosis complex (somatic or germline) associated renal neoplasms. The latter category is a heterogenous group with entities still being delineated. Eosinophilic solid and cystic renal cell carcinoma is the best-described entity, whereas, eosinophilic vacuolated tumor is a proposed entity, and the remaining tumors are currently grouped together under the umbrella of tuberous sclerosis complex/mammalian target of rapamycin –related renal neoplasms. The entities described in this review are often diagnostic considerations when evaluating renal mass tissue on biopsy or resection. For example, Xp11.2 translocation renal cell carcinoma is in the differential when a tumor has clear cell cytology and papillary architecture and occurs in a young or middle-aged patient. In contrast, tuberous sclerosis complex –related neoplasms often enter the differential for tumors with eosinophilic cytology. This review provides an overview of the clinical, gross, microscopic, immunohistochemical, genetic, and molecular alterations in key renal neoplasms occurring more commonly in females; differential diagnoses are also discussed regardless of sex predilection.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
夏炖鱿鱼完成签到,获得积分10
2秒前
大模型应助勤奋雨采纳,获得10
3秒前
3秒前
4秒前
八八九九九1完成签到,获得积分10
5秒前
mbf关闭了mbf文献求助
6秒前
善学以致用应助谨慎太兰采纳,获得10
6秒前
7秒前
xu发布了新的文献求助10
8秒前
9秒前
夏炖鱿鱼发布了新的文献求助10
10秒前
10秒前
MJyhy发布了新的文献求助10
11秒前
花花应助sekidesu采纳,获得10
11秒前
彭于晏应助欢呼芷雪采纳,获得10
11秒前
11秒前
的微博发布了新的文献求助10
14秒前
14秒前
英俊的铭应助王炎欣采纳,获得10
14秒前
糖糖糖唐完成签到,获得积分10
16秒前
艾欧比发布了新的文献求助10
18秒前
NexusExplorer应助科研通管家采纳,获得10
19秒前
zdh发布了新的文献求助20
19秒前
Hello应助科研通管家采纳,获得10
19秒前
JamesPei应助科研通管家采纳,获得10
19秒前
SciGPT应助科研通管家采纳,获得10
19秒前
上官若男应助科研通管家采纳,获得10
20秒前
orixero应助科研通管家采纳,获得10
20秒前
落落发布了新的文献求助10
20秒前
Akim应助科研通管家采纳,获得10
20秒前
20秒前
wwnd完成签到,获得积分10
20秒前
llj发布了新的文献求助10
20秒前
20秒前
21秒前
21秒前
21秒前
谨慎太兰完成签到,获得积分20
22秒前
MJyhy完成签到,获得积分10
23秒前
高分求助中
좌파는 어떻게 좌파가 됐나:한국 급진노동운동의 형성과 궤적 2500
Sustainability in Tides Chemistry 1500
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Cognitive linguistics critical concepts in linguistics 800
Threaded Harmony: A Sustainable Approach to Fashion 799
Livre et militantisme : La Cité éditeur 1958-1967 500
氟盐冷却高温堆非能动余热排出性能及安全分析研究 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3051401
求助须知:如何正确求助?哪些是违规求助? 2708725
关于积分的说明 7413996
捐赠科研通 2352918
什么是DOI,文献DOI怎么找? 1245385
科研通“疑难数据库(出版商)”最低求助积分说明 605649
版权声明 595846