Herein, the split Hopkinson pressure bar (SHPB) technique is used to investigate the effect of aging-treatment on mechanical properties and microstructural evolution of extruded ZK60 (Mg-5.8Zn-0.72Zr) alloy under dynamic compression at a strain rate of 1000 s −1 . The experimental results reveal that the amount of precipitated MgZn and MgZn 2 phases gradually increased with increasing aging time, which led to an increase of 60.4% in the peak flow stress under the peak aging condition due to precipitation strengthening. EBSD and TEM results demonstrate that {10[Formula: see text] 2} extension twinning plays a critical role in determining the deformation mechanism. Furthermore, the extension twinning boundaries and precipitated phases during the aging process hindered the dislocations slip during deformation and significantly influenced the dislocation strengthening.