Research Progresses on Chemical Components and Pharmacological Functions of <i>Aconitum vilmorinianum</i> Kom

乌头 毛茛科 药用植物 中医药 药理学 传统医学 毒性 生物碱 生物 毒理 计算生物学 医学 植物 内科学 病理 替代医学
作者
Li Yi-guo,Mou Fengjuan,Li Kun-zhi
标识
DOI:10.57237/j.mrf.2023.03.004
摘要

Aconitum vilmorinianum (Ranunculaceae, Aconitum) is an important traditional Chinese medicine in southwest China. It contains diterpenoid alkaloids such as yunaconitine, which have many functions, such as antirheumatic activity, improvement in human meridians, relief of swelling and pain, activation of the blood circulation, and inhibition of tumor growth. Scholars at home and abroad have carried out a lot of research work around the biology, chemical composition, pharmacological action, toxicity of Aconitine, etc. According to literature research, Yunnan is the province with the richest plant resources of the genus Aconitum. A. vilmorinianum contains 47 kinds of alkaloids, as well as flavonoids, sterols and other non alkaloid ingredients that are beneficial to human body. The research on standardized seed seedlings, planting techniques, and harvesting provides a scientific basis for the standardized production of A. vilmorinianum. The research on tissue culture, alkaloid metabolism pathways, screening of internal reference genes, and identification of blue flower genes provides reference for the application of biotechnology in A. vilmorinianum. The research on analgesic, anti-inflammatory, immune regulation, anti-tumor, and toxicity of A. vilmorinianum provides scientific reference for its clinical and development applications. Propose research directions on the pharmacological activity, resource protection, standardized production, and toxicity of A. vilmorinianum, providing reference for the comprehensive development and utilization of A. vilmorinianum.

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