Iridium‐Catalyzed Asymmetric CH Functionalization

Abstract Iridium catalysis is one of the major synthetic protocols in CH functionalization. In particular, it has been used to realize significant achievements in enantioselective transformations. This article describes Ir‐catalyzed enantioselective reactions initiated by CH bond cleavage. Various CH alkylations using alkenes are mainly discussed as an atom‐economical strategy. As a recent advancement, the introduction of heteroatom functionality by CH activation, such as CH borylation, silylation, and amidation, is also mentioned.