Efficient Eu3+-Integrated UiO-66 Probe for Ratiometric Fluorescence Sensing of Styrene and Cyclohexanone

The development of probes with sensitive and prompt detection of volatile organic compounds (VOCs) is of great importance for protecting human health and public security. Herein, we successfully prepared a series of bimetallic lanthanide metal-organic framework (Eu/Zr-UiO-66) by incorporating Eu³⁺ for fluorescence sensing of VOCs (especially styrene and cyclohexanone) using a one-pot method. Based on the multiple fluorescence signal responses of Eu/Zr-UiO-66 toward styrene and cyclohexanone, a ratiometric fluorescence probe using (I₆₁₇/I₃₂₀) and (I₆₁₇/I₃₃₀) as output signals was developed to recognize styrene and cyclohexanone, respectively. Benefitting from the multiple fluorescence response, the limits of detection (LODs) of Eu/Zr-UiO-66 (1:9) for styrene and cyclohexanone were 1.5 and 2.5 ppm, respectively. These are among the lowest reported levels for MOF-based sensors, and this is the first known material for fluorescence sensing of cyclohexanone. Fluorescence quenching by styrene was mainly owing to the large electronegativity of styrene and fluorescence resonance energy transfer (FRET). However, FRET was accounted for fluorescence quenching by cyclohexanone. Moreover, Eu/Zr-UiO-66 (1:9) exhibited good anti-interference ability and recycling performance for styrene and cyclohexanone. More importantly, the visual recognition of styrene and EB vapor can be directly realized with the naked eyes using Eu/Zr-UiO-66 (1:9) test strips. This strategy provides a sensitive, selective, and reliable method for the visual sensing of styrene and cyclohexanone.