Spirocyclic polyketides from the marine fungus Talaromyces sp. CX11

Three new spirocyclic polyketides, talaromyacins A – C, were identified from the endophytic fungus Talaromyces sp. CX11. Their structures including absolute configurations were determined by extensive spectroscopic analysis, Snatzke's method and quantum chemical calculations. Talaromyacin A is identical to the known sequoiamonascin A, for which a structural revision is required.