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Exploring the chain mediating roles of frailty and depressive symptoms in the relationship between pain and cognitive function among nursing home older adults

认知 调解 联想(心理学) 抑郁症状 医学 认知功能衰退 慢性疼痛 人口 临床心理学 老年学 心理学 精神科 痴呆 内科学 疾病 心理治疗师 环境卫生 政治学 法学
作者
Xia Zhao,Huaxin Si
出处
期刊:Psychogeriatrics [Wiley]
卷期号:24 (2): 426-432
标识
DOI:10.1111/psyg.13089
摘要

Abstract Background The prevalence of cognitive decline is high among nursing home older adults. Pain is a vital factor in cognitive function. Furthermore, the current literature lacks the complex association between pain, frailty, depressive symptoms, and cognitive function. The aim of this study was to explore the chain mediating roles of frailty and depressive symptoms in the association between pain and cognitive function among nursing home older adults. Methods This is a population‐based cross‐sectional study, conducted in China, of 210 nursing home older adults aged 64–98 years old, who completed the measurements of sociodemographic information, pain, frailty, depressive symptoms, and cognitive function. Mediation analyses tested the indirect effect of frailty and depressive symptoms in the relationship between pain and cognitive function by PROCESS macro. Results Pain, frailty, as well as depressive symptoms, were negatively related to cognitive function. Frailty mediated the association between pain and cognitive function. Importantly, mediation analyses showed that frailty and depressive symptoms acted as sequential mediators of pain and cognitive function. Conclusions These findings have crucial clinical implications, as they suggest targeting physiological and psychological factors in older adults with chronic pain to alleviate cognitive decline.
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