Electrochemical 1,3‐Oxofluorination of Gem‐Difluoro Cyclopropanes: Approach to α‐CF3‐Substituted Carbonyl Compounds

Abstract An electrochemical methodology for the construction of α ‐CF 3 ‐substituted carbonyl compounds in moderate to good yields under exogenous metal and oxidant‐free conditions has been developed. The protocol involves the single‐electron oxidation of the aryl ring to generate a radical cation followed by a three‐electron S N 2 reaction resulting in the formation of α ‐CF 3 substituted ketones.