Response by Sun et al to Letter Regarding Article, “Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2”

HomeCirculationVol. 147, No. 20Response by Sun et al to Letter Regarding Article, “Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2” No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextResponse by Sun et al to Letter Regarding Article, “Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2” Ling-Yue Sun, Yu-Yan Lyu and Jun Pu Ling-Yue SunLing-Yue Sun Department of Cardiology, Renji Hospital, School of Medicine, State Key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China. *L.-Y. Sun and Y.-Y. Lyu contributed equally. Search for more papers by this author , Yu-Yan LyuYu-Yan Lyu Department of Cardiology, Renji Hospital, School of Medicine, State Key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China. *L.-Y. Sun and Y.-Y. Lyu contributed equally. Search for more papers by this author and Jun PuJun Pu https://orcid.org/0000-0003-2240-5108 Department of Cardiology, Renji Hospital, School of Medicine, State Key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China. Search for more papers by this author Originally published15 May 2023https://doi.org/10.1161/CIRCULATIONAHA.123.064232Circulation. 2023;147:1562–1563"Response by Sun et al to Letter Regarding Article, “Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2”." Circulation, 147(20), pp. 1562–1563Footnotes*L.-Y. Sun and Y.-Y. Lyu contributed equally.Circulation is available at www.ahajournals.org/journal/circReferences1. Sun LY, Lyu YY, Zhang HY, Shen Z, Lin GQ, Geng N, Wang YL, Huang L, Feng ZH, Guo X, et al. Nuclear receptor NR1D1 regulates abdominal aortic aneurysm development by targeting the mitochondrial tricarboxylic acid cycle enzyme aconitase-2.Circulation. 2022; 146:1591–1609. doi: 10.1161/CIRCULATIONAHA.121.057623LinkGoogle Scholar2. Nagaraj R, Sharpley MS, Chi F, Braas D, Zhou Y, Kim R, Clark AT, Banerjee U. Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation.Cell. 2017; 168:210–223.e11. doi: 10.1016/j.cell.2016.12.026CrossrefMedlineGoogle Scholar3. Liu X, Si W, He L, Yang J, Peng Y, Ren J, Liu X, Jin T, Yu H, Zhang Z, et al. The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry.Signal Transduct Target Ther. 2021; 6:375. doi: 10.1038/s41392-021-00774-2CrossrefMedlineGoogle Scholar4. Bayliak MM, Lushchak VI. Pleiotropic effects of alpha-ketoglutarate as a potential anti-ageing agent.Ageing Res Rev. 2021; 66:101237. doi: 10.1016/j.arr.2020.101237CrossrefMedlineGoogle Scholar5. Zhao Y, Lu X, Wan F, Gao L, Lin N, He J, Wei L, Dong J, Qin Z, Zhong F, et al. Disruption of circadian rhythms by shift work exacerbates reperfusion injury in myocardial infarction.J Am Coll Cardiol. 2022; 79:2097–2115. doi: 10.1016/j.jacc.2022.03.370CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails May 16, 2023Vol 147, Issue 20 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.123.064232PMID: 37186684 Originally publishedMay 15, 2023 PDF download Advertisement