鞘氨醇激酶1
纤维化
巨噬细胞极化
医学
鞘氨醇
巨噬细胞
肝纤维化
细胞生物学
1-磷酸鞘氨醇
癌症研究
内科学
生物
遗传学
受体
体外
作者
Xin Ding,Xiang Zhang,Jiafan Cao,Shiyun Chen,Yinghua Chen,Keng Yuan,Bo Chen,Guizhi Yang,Shengwen Li,Jundong Yang,Guixiang Wang,Frank Tacke,Tian Lan
标识
DOI：10.1016/j.jcmgh.2024.101406
摘要
Sphingosine kinase 1 (SphK1) has distinct roles in the activation of Kupffer cells (KCs) and hepatic stellate cells (HSCs) in liver fibrosis. Here, we aim to investigate the roles of SphK1 on hepatic macrophage recruitment and polarization in liver fibrosis.
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