清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Solid Breast Lesions: Clinical Experience with US-guided Diffuse Optical Tomography Combined with Conventional US

医学 预测值 试验预测值 活检 核医学 病变 金标准(测试) 血红蛋白 放射科 正谓词值 漫反射光学成像 机构审查委员会 内科学 病理 断层摄影术 外科
作者
Wenxiang Zhi,Gu X,Min Qin,Peihao Yin,Xia Sheng,Sizhi Paul Gao,Qi Li
出处
期刊:Radiology [Radiological Society of North America]
卷期号:265 (2): 371-378 被引量:20
标识
DOI:10.1148/radiol.12120086
摘要

To prospectively investigate the clinical efficacy of using diffuse optical tomography (DOT) and ultrasonographic (US) localization with conventional US to differentiate malignant solid breast lesions from those that are benign.The study was approved by the institutional review board and all patients provided written informed consent. One hundred two consecutive women (mean age, 43 years; range, 18-86 years) who were referred for open biopsy with 136 breast lesions underwent conventional US and DOT with US localization. Total hemoglobin concentration and oxygen saturation were measured for each breast lesion. Sensitivity, specificity, overall accuracy, positive predictive value, and negative predictive value were determined with surgical pathologic examination results as the verification standard.Of the 136 biopsied lesions, 54 were carcinomas and 82 were benign. The average total hemoglobin concentration in the malignant group was 223.3 μmol/L±55.8 (standard deviation), and the average hemoglobin concentration in the benign group was 122.5 μmol/L±80.6 (P=.005). When the maximum hemoglobin concentration of 137.8 μmol/L was used as the threshold value, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of DOT with US localization were 96.3%, 65.9%, 65.0%, 96.4%, and 76.5%, respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of conventional US were 96.3%, 92.6%, 89.7%, 97.4%, and 93.4%, respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of conventional US combined with DOT were 100%, 93.9%, 91.5%, 100%, and 96.3%, respectively.US-guided DOT combined with conventional US improves accuracy compared with DOT alone.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Young完成签到 ,获得积分10
1秒前
xue完成签到 ,获得积分10
3秒前
丘比特应助科研通管家采纳,获得10
4秒前
林利芳完成签到 ,获得积分0
44秒前
研友_8y2G0L完成签到,获得积分10
47秒前
48秒前
53秒前
1分钟前
小焦儿发布了新的文献求助10
1分钟前
1分钟前
吃的饭广泛应助小焦儿采纳,获得10
1分钟前
谭平完成签到 ,获得积分10
1分钟前
科研的豪哥完成签到 ,获得积分10
1分钟前
小焦儿完成签到,获得积分10
1分钟前
完美梨愁完成签到 ,获得积分10
1分钟前
wanci应助无限的以亦采纳,获得10
1分钟前
糟糕的翅膀完成签到,获得积分10
1分钟前
creep2020完成签到,获得积分10
2分钟前
谭凯文完成签到 ,获得积分10
2分钟前
lorentzh完成签到,获得积分10
2分钟前
2分钟前
YX完成签到 ,获得积分10
2分钟前
2分钟前
Sandy应助Am采纳,获得20
2分钟前
桐桐应助嘿嘿嘿侦探社采纳,获得10
2分钟前
ycool完成签到 ,获得积分10
2分钟前
小强完成签到 ,获得积分10
2分钟前
大树完成签到 ,获得积分10
3分钟前
3分钟前
3分钟前
3分钟前
3分钟前
3分钟前
naiyantang完成签到 ,获得积分10
4分钟前
科研通AI2S应助科研通管家采纳,获得10
4分钟前
周常通完成签到,获得积分10
4分钟前
4分钟前
xiaosui完成签到 ,获得积分10
4分钟前
lingling完成签到 ,获得积分10
4分钟前
浪麻麻完成签到 ,获得积分10
4分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968521
求助须知:如何正确求助?哪些是违规求助? 3513341
关于积分的说明 11167298
捐赠科研通 3248700
什么是DOI,文献DOI怎么找? 1794417
邀请新用户注册赠送积分活动 875030
科研通“疑难数据库(出版商)”最低求助积分说明 804664