马来酰亚胺
环丙烷
细胞毒性
化学
立体化学
组合化学
有机化学
生物化学
戒指(化学)
体外
作者
Wenbo Wang,Haotian Lu,Mengsi Zhang,Hailong Ma,Xiaoyu Cheng,Yun Ding,Aiguo Hu
摘要
Maleimide-based enediynes with cyclopropane moieties show enhanced radical character by taking advantage of radical clock reactions. They are highly effecient antitumor agents under both normoxic and hypoxic conditions.
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