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HomeCirculation ResearchAhead of PrintTitin-Based Force Modulates Cardiac Thick and Thin Filaments No AccessLetterRequest AccessAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessTitin-Based Force Modulates Cardiac Thick and Thin Filaments Anthony L. Hessel, Michel N. Kuehn, Nichlas M. Engels, Devin L. Nissen, Johanna K. Freundt, Weikang Ma, Thomas C. Irving and Wolfgang A. Linke Anthony L. HesselAnthony L. Hessel Correspondence to: Anthony L. Hessel, PhD, Institute of Physiology II, University of Münster, Robert-Koch-Str. 27b, D-48149 Münster, Germany Email E-mail Address: [email protected] https://orcid.org/0000-0003-4278-4221 Institute of Physiology II, University of Münster, Germany (A.L.H., M.N.K., J.K.F., W.A.L.). , Michel N. KuehnMichel N. Kuehn https://orcid.org/0000-0001-7232-2517 Institute of Physiology II, University of Münster, Germany (A.L.H., M.N.K., J.K.F., W.A.L.). , Nichlas M. EngelsNichlas M. Engels https://orcid.org/0000-0003-0613-0925 Department of Cellular and Molecular Medicine, The University of Arizona, Tucson (N.M.E.). , Devin L. NissenDevin L. Nissen BioCAT, Department of Biology, Illinois Institute of Technology, Chicago (D.L.N., W.M., T.C.I.). , Johanna K. FreundtJohanna K. Freundt https://orcid.org/0009-0009-1356-7624 Institute of Physiology II, University of Münster, Germany (A.L.H., M.N.K., J.K.F., W.A.L.). , Weikang MaWeikang Ma https://orcid.org/0000-0001-9535-7114 BioCAT, Department of Biology, Illinois Institute of Technology, Chicago (D.L.N., W.M., T.C.I.). , Thomas C. IrvingThomas C. Irving https://orcid.org/0000-0003-4848-3323 BioCAT, Department of Biology, Illinois Institute of Technology, Chicago (D.L.N., W.M., T.C.I.). and Wolfgang A. LinkeWolfgang A. Linke Wolfgang A. Linke, PhD, Institute of Physiology II, University of Münster, Robert-Koch-Str. 27b, D-48149 Münster, Germany Email E-mail Address: [email protected] https://orcid.org/0000-0003-0801-3773 Institute of Physiology II, University of Münster, Germany (A.L.H., M.N.K., J.K.F., W.A.L.). Originally published14 Mar 2024https://doi.org/10.1161/CIRCRESAHA.123.323988Circulation Research. 2024;0FootnotesFor Sources of Funding and Disclosures, see page xxx.Correspondence to: Anthony L. Hessel, PhD, Institute of Physiology II, University of Münster, Robert-Koch-Str. 27b, D-48149 Münster, Germany Email Anthony.hessel@uni-muenster.deWolfgang A. Linke, PhD, Institute of Physiology II, University of Münster, Robert-Koch-Str. 27b, D-48149 Münster, Germany Email wlinke@uni.muenster.de eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.123.323988PMID: 38482667 Originally publishedMarch 14, 2024 Keywordscalciummuscle, skeletalmyofibrilssarcomeresstroke volumePDF download Advertisement SubjectsBasic Science ResearchMyocardial BiologyPhysiology