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HomeStrokeAhead of PrintThe Ever-Evolving Concept of the Neurovascular Unit No AccessArticle CommentaryRequest AccessAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessArticle CommentaryRequest AccessThe Ever-Evolving Concept of the Neurovascular Unit Nabil J. Alkayed and Marilyn J. Cipolla Nabil J. AlkayedNabil J. Alkayed Correspondence to: Nabil J. Alkayed, MD, PhD, Department of Anesthesiology and Perioperative Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239. Email E-mail Address: [email protected] https://orcid.org/0000-0002-3489-4730 Department of Anesthesiology and Perioperative Medicine, Knight Cardiovascular Institute, Portland, OR (N.J.A.). Search for more papers by this author and Marilyn J. CipollaMarilyn J. Cipolla https://orcid.org/0000-0002-9172-5941 Department of Neurological Sciences, Larner College of Medicine at The University of Vermont, Burlington (M.J.C.). Department of Electrical and Biomedical Engineering, College of Engineering and Mathematical Sciences, Burlington, VT (M.J.C.). Search for more papers by this author Originally published3 Jul 2023https://doi.org/10.1161/STROKEAHA.123.042705Stroke. 2023;0FootnotesThe opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.For Sources of Funding and Disclosures, see page XXX.Correspondence to: Nabil J. Alkayed, MD, PhD, Department of Anesthesiology and Perioperative Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239. Email [email protected]edu eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/STROKEAHA.123.042705PMID: 37395105 Originally publishedJuly 3, 2023 Keywordsneurovascular couplingstrokeblood-brain barrierPDF download Advertisement SubjectsBasic Science ResearchMechanisms