Rhodium‐Catalyzed Selective C−H Bond Functionalization of Quinolines

Abstract In the last two decades, rhodium‐based catalysts have been used extensively for the sp 2 and sp 3 C−H bond activation/functionalization of various arenes, heteroarenes, and aliphatic compounds, respectively. For quinoline functionalization rhodium has been used significantly as compared to other transition metals such as cobalt, copper, ruthenium, palladium and iridium. In this Minireview the progress on rhodium‐catalyzed selective functionalization of quinoline N ‐oxides and 8‐methylquinolines via sp 2 and sp 3 C−H bond activation, respectively have been highlighted. The main focus is on reaction mechanism, substrate scope, and positional selectivity.