托法替尼
银屑病性关节炎
医学
阿达木单抗
Janus激酶抑制剂
安慰剂
皮肤病科
抗风湿药物
关节炎
银屑病
贾纳斯激酶
药理学
内科学
抗风湿药
类风湿性关节炎
替代医学
病理
细胞因子
作者
Philip J. Mease,Stephen Hall,Oliver FitzGerald,Désirée van der Heijde,Joseph F. Merola,Francisco Ávila‐Zapata,Dorota Cieślak,Daniela Graham,Cunshan Wang,Sujatha Menon,Thijs Hendrikx,Keith S. Kanik
标识
DOI:10.1056/nejmoa1615975
摘要
Tofacitinib is an oral Janus kinase inhibitor that is under investigation for the treatment of psoriatic arthritis. We evaluated tofacitinib in patients with active psoriatic arthritis who previously had an inadequate response to conventional synthetic disease-modifying antirheumatic drugs (DMARDs).
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