肝素
肥大细胞
细胞质
化学
功能(生物学)
细胞生物学
药理学
免疫学
生物
生物化学
作者
James L. Zehnder,Stephen J. Galli
出处
期刊:Nature
[Springer Nature]
日期:1999-08-01
卷期号:400 (6746): 714-715
被引量:37
摘要
A commonly used compound in medicine is heparin, which prevents the formation of blood clots. Despite its widespread use, the physiological function of heparin has been enigmatic — until now. Two groups have generated mice that lack heparin, and they find that its function is to regulate the types and amounts of other biologically active mediators in granules found within the cytoplasm of mast cells.
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