Pseudoxanthoma elasticum (PXE) is a disease characterized by aberrant mineralization of soft tissue and fragmentation of elastic fibres. It is often difficult to distinguish PXE clinically from pseudoxanthoma elasticum‐like papillary dermal elastolysis (PXE‐like PDE). However, we have identified that the dermoscopic findings in PXE include coalescing and reticulated yellow‐white clods on a light purple‐red background, whereas the dermoscopic findings in PXE‐like PDE lack such a coloured background. To our knowledge, this is the first detailed description of dermoscopic differences between PXE and PXE‐like PDE.