自噬
程序性细胞死亡
细胞
细胞生物学
癌症研究
肺癌
溶酶体
化学
生物
医学
细胞凋亡
病理
生物化学
酶
作者
Dong Xian,Xiyu Liu,Lin Dongliang,Lian Zhang,Yue Wu,Yuzhen Chang,Mingming Jin,Gang Huang
出处
期刊:Phytomedicine
[Elsevier]
日期:2024-07-20
卷期号:133: 155872-155872
被引量:1
标识
DOI:10.1016/j.phymed.2024.155872
摘要
Non-small cell lung cancer (NSCLC) accounts for 85 % of lung cancer, becoming the most mortality of all cancers globally. Blockage of autophagy in NSCLC represents a promising therapeutic strategy that inhibits angiogenesis and overcomes drug resistance. Natural ingredients in anti-tumor adjuvants are increasingly reported to promote cell death with less side effects and the potential to increase chemotherapeutic drugs sensitivity. Baicalin, a Scutellaria baicalensis-extracted flavonoid glycoside, is reported to induce death of NSCLC cells, however, its effects on autophagy in NSCLC cells remain unclear.
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