酰基转移酶
二酰甘油激酶
肥胖
结直肠癌
癌症
内科学
医学
生物
内分泌学
癌症研究
生物化学
基因
酶
生物合成
蛋白激酶C
作者
Jenisha Ghimire,Morgan E. Collins,Patricia Snarski,Angelle N. King,Emmanuelle Ruiz,Rida Iftikhar,Harrison M. Penrose,Krzysztof Moroz,Tyler Rorison,Melody Baddoo,Muhammad Naeem,Arnold H. Zea,Scott T. Magness,Erik Flemington,Susan E. Crawford,Suzana D. Savkovic
标识
DOI：10.1053/j.gastro.2024.09.011
摘要
The obesity epidemic is associated with increased colon cancer progression. As lipid droplets (LDs) fuel tumor growth, we aim to determine the significance of diacyltransferases, DGAT1/2, responsible for LDs biogenesis, in obesity-mediated colonic tumorigenesis.
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