羟基烷酸
生物塑料
生化工程
生产(经济)
生物技术
制浆造纸工业
商业化
产量(工程)
发酵
业务
食品科学
化学
废物管理
生物
经济
材料科学
工程类
细菌
遗传学
宏观经济学
营销
冶金
作者
Sook Wei Lim,Jibrail Kansedo,Inn Shi Tan,Yie Hua Tan,Jobrun Nandong,Man Kee Lam,Clarence M. Ongkudon
标识
DOI:10.1016/j.procbio.2023.05.013
摘要
With the rising interest in developing polyhydroxyalkanoate (PHA) bioplastics as an auspicious substitute for conventional plastics, the exploitation of low-cost oil substrates for PHA biosynthesis has become popular recently. In view of the paucity of feasibility studies on lipid-based PHA production, this paper aims to provide an overview of the PHA production from diverse lipid-rich sources, covering the PHA production efficiencies using different plausible fermentation strategies and the key influencing factors for oil-based PHA production. Considering the high conversion efficiency (97.5% of the theoretical PHA yield), direct fermentation of oil has shown great promise for PHA industrialization. Plant oils which could achieve a high PHA yield (0.25–0.77 g/g) are better carbon sources than waste cooking oil (0.15–0.28 g/g). In addition to providing information on the potential enhancement tools (i.e., mixed cultures, metabolic engineering, and kinetic studies) for lipid-based PHA production, this paper also reviews the techno-economic and life cycle assessment of PHA production in comparison to the conventional plastics. Besides, technical challenges and future perspectives for the commercialization of oil-based PHA production have been discussed (specifically targeting on the concerns of inconsistent production efficiency, complex recovery process, and high production cost), offering further insights towards developing a sustainable circular economy.
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