聚四氟乙烯
内膜增生
支架
管腔(解剖学)
膜
医学
生物医学工程
外科
材料科学
复合材料
化学
生物化学
内科学
平滑肌
作者
Roberta Cassano,Paolo Perri,Antonio Esposito,Francesco Intrieri,Roberta Del Sole,Federica Curcio,Sonia Trombino
出处
期刊:Membranes
[Multidisciplinary Digital Publishing Institute]
日期:2023-02-17
卷期号:13 (2): 240-240
被引量:14
标识
DOI:10.3390/membranes13020240
摘要
Coated stents are defined as innovative stents surrounded by a thin polymer membrane based on polytetrafluoroethylene (PTFE)useful in the treatment of numerous vascular pathologies. Endovascular methodology involves the use of such devices to restore blood flow in small-, medium- and large-calibre arteries, both centrally and peripherally. These membranes cross the stent struts and act as a physical barrier to block the growth of intimal tissue in the lumen, preventing so-called intimal hyperplasia and late stent thrombosis. PTFE for vascular applications is known as expanded polytetrafluoroethylene (e-PTFE) and it can be rolled up to form a thin multilayer membrane expandable by 4 to 5 times its original diameter. This membrane plays an important role in initiating the restenotic process because wrapped graft stent could be used as the treatment option for trauma devices during emergency situations and to treat a number of pathological vascular disease. In this review, we will investigate the multidisciplinary techniques used for the production of e-PTFE membranes, the advantages and disadvantages of their use, the innovations and the results in biomedical and surgery field when used to cover graft stents.
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