PhI(OAc)2/KI mediated 1,2-acetoxysulfenylation of alkenes: facile synthesis of β-acetoxysulfides

A convenient method for 1,2-acetoxysulfenylation of alkenes using disulfide promoted by (diacetoxyiodo)benzene (PhI(OAc)2, DIB)/KI was developed. The reaction is highly regioselective for styrene derivatives while aliphatic alkenes lead to a mixture of two regioisomers.