A facile solid-phase synthesis of Baylis–Hillman products from polymeric selenium reagents

Treatment of lithio derivatives of polystyrene-supported methyl α-selenopropionate, 2-selenopropiophenone, 1-selenoethyl phenyl sulfone and diethyl 1-selenoethylphosphonate with aldehydes respectively, followed by cleavage from the polymer by oxidation-elimination with 30% hydrogen peroxide efficiently afforded Baylis–Hillman products in good yields and high purities.