Clinical management of canine babesiosis

Journal of Veterinary Emergency and Critical CareVolume 20, Issue 1 p. 77-89 Clinical management of canine babesiosis Ashley L. Ayoob DVM, DACVIM, Ashley L. Ayoob DVM, DACVIM Department of Emergency and Critical Care Medicine, Animal Medical Center, New York, NY 10065Search for more papers by this authorSusan G. Hackner BVSc, MRCVS, DACVIM, DACVECC, Susan G. Hackner BVSc, MRCVS, DACVIM, DACVECC Department of Emergency and Critical Care Medicine, Animal Medical Center, New York, NY 10065Search for more papers by this authorJennifer Prittie DVM, DACVIM, DACVECC, Jennifer Prittie DVM, DACVIM, DACVECC Department of Emergency and Critical Care Medicine, Animal Medical Center, New York, NY 10065Search for more papers by this author Ashley L. Ayoob DVM, DACVIM, Ashley L. Ayoob DVM, DACVIM Department of Emergency and Critical Care Medicine, Animal Medical Center, New York, NY 10065Search for more papers by this authorSusan G. Hackner BVSc, MRCVS, DACVIM, DACVECC, Susan G. Hackner BVSc, MRCVS, DACVIM, DACVECC Department of Emergency and Critical Care Medicine, Animal Medical Center, New York, NY 10065Search for more papers by this authorJennifer Prittie DVM, DACVIM, DACVECC, Jennifer Prittie DVM, DACVIM, DACVECC Department of Emergency and Critical Care Medicine, Animal Medical Center, New York, NY 10065Search for more papers by this author First published: 08 February 2010 https://doi.org/10.1111/j.1476-4431.2009.00489.xCitations: 49 Address correspondence and reprint requests to Dr. Ashley Ayoob, Department of Emergency and Critical Care Medicine, The Animal Medical Center, 510 East 62nd St, New York, NY 10065, USA. Email: [email protected] The authors declare no conflicts of interest. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Objective – To review and summarize current information regarding epidemiology, pathogenesis, and pathophysiology leading to the various clinical syndromes associated with canine babesiosis. Diagnosis, treatment, preventative strategies, and zoonotic implications are discussed. Etiology – Babesiosis is caused by hemoprotozoa of the genus Babesia. Numerous species of Babesia exist worldwide. An increased incidence of babesiosis is described, especially in North America. The babesial organism spends the majority of its life cycle within the erythrocyte of the definitive host, resulting in hemolysis, with or without systemic complications. Diagnosis – Definitive diagnosis depends on direct visualization of the organism on blood smear or polymerase chain reaction. A positive serologic antibody test indicates exposure with or without active infection. Therapy – Antiprotozoal drugs, antimicrobials, and supportive care are the mainstays of babesiosis therapy. Prognosis – Prognosis depends on the severity of disease, which in turn depends on both organism and host factors. Clinical syndromes associated with a poorer prognosis include red biliary syndrome, acute renal failure, acute respiratory distress syndrome, neurologic dysfunction, acute pancreatitis, cardiac dysfunction, and hypoglycemia. Citing Literature Volume20, Issue1February 2010Pages 77-89 RelatedInformation