效应器
黄单胞菌
生物
毒力
三型分泌系统
分泌物
遗传学
微生物学
细胞生物学
细菌
基因
生物化学
出处
期刊:Annual Review of Phytopathology
[Annual Reviews]
日期:2010-07-01
卷期号:48 (1): 419-436
被引量:877
标识
DOI:10.1146/annurev-phyto-080508-081936
摘要
Xanthomonads are bacterial plant pathogens that cause diseases on many plant species, including important crops. Key to pathogenicity of most Xanthomonas pathovars is a Hrp-type III secretion (T3S) system that translocates effector proteins into plant cells. Within the eukaryotic cell, the effectors are thought to perform a variety of tasks to support bacterial virulence, proliferation, and dissemination. We are only beginning to understand the host targets of different effectors. The largest effector family found in Xanthomonas spp. is the AvrBs3/PthA or TAL (transcription activator-like) family. TAL effectors act as transcriptional activators in the plant cell nucleus. Specificity of TAL effectors is determined by a novel modular DNA-binding domain. Here, we describe the discovery of TAL effectors and their structure, activity, and host targets.
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