医学
肝细胞癌
代谢综合征
肝切除术
内科学
倾向得分匹配
胃肠病学
入射(几何)
回顾性队列研究
肿瘤科
外科
切除术
肥胖
光学
物理
作者
Yunhong Tian,Tie Li,Shouliang Qi,Hani Alhourani,Binyu Luo,Junjie Chenqin,Qizhong Fu,Yong Peng,Jian-Lin Wu
摘要
Background and Objectives The impact of metabolic syndrome (MetS) on surgical outcome, mostly in patients with HBV-related hepatocellular carcinoma (HCC) who underwent hepatectomy. Methods A propensity score matching analysis was conducted. Patients were categorized into two groups MetS-related hepatocellular carcinoma (MetS-HCC) and 1:1 matched non-MetS-related HCC (non-MetS-HCC). Surgical outcomes were compared between the two groups. Results Seventy-four MetS-HCC patients and 74 propensity score-matched non-MetS-HCC patients were selected for analysis. The incidence of surgical site infection was higher in the MetS-HCC group than in the non-MetS-HCC group (12.16% vs 0%, P < .005). There was no difference in the recurrence-free survival and overall survival between patients in the MetS-HCC group and in non-MetS-HCC group (P > .05). Microvascular invasion and severe postoperative complications were independent risk factors for recurrence-free survival and overall survival. Conclusions Hepatectomy for patients with mostly HBV-related HCC in the presence of MetS can result in a higher rate of postoperative surgical site infection compared with those in the absence of MetS, but long-term survival rates are comparable.
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