树枝状大分子
牙本质
再矿化
牙齿再矿化
唾液
化学
磷酸盐
基质(化学分析)
牙科
脱盐
生物医学工程
核化学
色谱法
高分子化学
生物化学
氟化物
医学
无机化学
搪瓷漆
作者
Yajie Wen,Jichao Wang,Jun Luo,Jiaojiao Yang
出处
期刊:Heliyon
[Elsevier]
日期:2020-12-01
卷期号:6 (12): e05886-e05886
被引量:4
标识
DOI:10.1016/j.heliyon.2020.e05886
摘要
Various sealants have been developed to treat the exposure of dentinal tubules (DTs) and further dental hypersensitivity. Herein, the phosphate-terminated fourth generation polyamidoamine dendrimers (PAMAM-PO3H2) was successfully synthesized. Six duplicates of demineralized dentin and type I collagen matrix were incubated in artificial saliva solution with or without PAMAM-PO3H2 treatment at 37 °C for 2 weeks, respectively. The artificial saliva solution was replaced every day. These regenerated crystals on the surface of dentin and collagen matrix were confirmed to be hydroxyapatite (HAp). The approach thus demonstrates that PAMAM-PO3H2 can offer an efficient therapy for seal DTs in clinical dentistry.
科研通智能强力驱动
Strongly Powered by AbleSci AI