This paper investigated the catalytic activity of Pd/@-La2O3/AC catalyst in the selective hydrogenation of phenol. The special structure and the synergistic effect remarkably facilitate the high conversion of phenol. Focuses on the deactivation reason and regenerated methods of the used Pd/@-La2O3/AC catalyst, it showed that organics adsorption in the channel and the Pd nanoparticles agglomeration, the regenerated method of water wash solved the problem of organic matter blockage and residue to a certain extent.