吡罗昔康
生物利用度
药品
溶解度
差示扫描量热法
药代动力学
化学
色谱法
核化学
药理学
有机化学
医学
物理
热力学
病理
替代医学
作者
G. Mostafa,Abdullah S. Al-Dosseri,Abdullah A. Al‐Badr
出处
期刊:Profiles of Drug Substances, Excipients and Related Methodology
日期:2019-12-18
卷期号:: 199-474
被引量:6
标识
DOI:10.1016/bs.podrm.2019.10.007
摘要
A comprehensive profile of piroxicam including the nomenclatures, formulae, elemental composition, appearance, uses and applications. The methods which were utilized for the preparation of the drug substance and their respective schemes are outlined. The physical characteristics of the drug including the ionization constant, solubility, x-ray powder diffraction pattern, differential scanning calorimetry, thermal behavior and spectroscopic studies are described. The methods which were used for the analysis of the drug substance in bulk drug and/or in pharmaceutical formulations including the compendial, spectrophotometric, electrochemical and the chromatographic methods are reported. The stability, toxicity, pharmacokinetics, bioavailability, drug evaluation, comparison, in addition to compiled reviews on the drug substance are involved. Finally, more than four hundred and fifty references are listed at the end of this profile.
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