Experimental myopia in chickens induced by corneal astigmatism

屈光度 眼科 散光 子午线(天文学) 纤维接头 医学 角膜地形图 角膜 解剖 视力 光学 物理 天文
作者
Yung‐Feng Shih,Tzyy‐Chang Ho,Muh‐Shy Chen,Luke L. K. Lin,Peng‐Cherng Wang,Ping‐Kang Hou
出处
期刊:Acta Ophthalmologica [Wiley]
卷期号:72 (5): 597-601 被引量:14
标识
DOI:10.1111/j.1755-3768.1994.tb07185.x
摘要

Abstract Astigmatism has been suggested to be an important factor in the production and/or progression of myopia. Chickens have been used as a myopic animal model for several years. In the present investigation our aim was to evaluate the importance of surgically induced corneal astigmatism by peripheral corneal incision with compression suture in one eye, the right, of 3‐day‐old chicks. Vertical incision (2 mm) with compression suture (nylon 9‐0, one stitch) induces against‐the‐rule astigmatism, horizontal incision with compression induces with‐the‐rule astigmatism. Four groups were studied 1) with one vertical cut, 2) one horizontal cut, 3) two vertical cuts, 4) two horizontal cuts. The eyes were measured by caliper after 8 weeks. Eye enlargements were induced in all groups, however, less by one cut (astigmatism around 5 diopters) than by two cuts (astigmatism 10 diopters, or more). In the latter groups the pattern of equatorial eye enlargement dependend on the axis of the induced astigmatism, the greater elongation being associated with the strongest refracting corneal meridian. All considered, the results suggest that significant corneal astigmatism could be another factor in the production of myopia, possibly acting by way of optical degradation of retinal image quality.
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