Leucoagaricus orientiflavus is described as new from southwestern China. It is characterized by a yellow pileus lacking plicate striations toward the margin, pure white lamellae, yellowish stipe and context, subamygdaliform basidiospores that are dextrinoid and lack a germ pore, cylindrico-clavate cheilocystidia, and a cutis-type pileipellis made up of radially arranged subcylindrical hyphae.