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Two‐sample Mendelian randomization analysis identifies a causal association between atopic dermatitis and impetigo

特应性皮炎 医学 皮肤病科 古特曼量表 图书馆学 家庭医学 心理学 计算机科学 发展心理学
作者
Michael J. Diaz,Ross O’Hagan,Jasmine T. Tran,Emma Guttman‐Yassky,Benjamin Ungar
出处
期刊:International Journal of Dermatology [Wiley]
卷期号:63 (9)
标识
DOI:10.1111/ijd.17314
摘要

International Journal of DermatologyEarly View Letter to the Editor Two-sample Mendelian randomization analysis identifies a causal association between atopic dermatitis and impetigo Michael J. Diaz, Corresponding Author Michael J. Diaz [email protected] orcid.org/0000-0003-2291-8122 College of Medicine, University of Florida, Gainesville, FL, USASearch for more papers by this authorRoss O'Hagan, Ross O'Hagan orcid.org/0000-0002-2310-756X Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USASearch for more papers by this authorJasmine T. Tran, Jasmine T. Tran School of Medicine, Indiana University, Indianapolis, IN, USASearch for more papers by this authorEmma Guttman-Yassky, Emma Guttman-Yassky Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USASearch for more papers by this authorBenjamin Ungar, Benjamin Ungar Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USASearch for more papers by this author Michael J. Diaz, Corresponding Author Michael J. Diaz [email protected] orcid.org/0000-0003-2291-8122 College of Medicine, University of Florida, Gainesville, FL, USASearch for more papers by this authorRoss O'Hagan, Ross O'Hagan orcid.org/0000-0002-2310-756X Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USASearch for more papers by this authorJasmine T. Tran, Jasmine T. Tran School of Medicine, Indiana University, Indianapolis, IN, USASearch for more papers by this authorEmma Guttman-Yassky, Emma Guttman-Yassky Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USASearch for more papers by this authorBenjamin Ungar, Benjamin Ungar Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USASearch for more papers by this author First published: 23 June 2024 https://doi.org/10.1111/ijd.17314 Conflict of interest: E. Guttman-Yassky has received institutional grants from AbbVie, Celgene, Eli Lilly, Janssen, Dermavant, DS Biopharma, Novartis, Pfizer, Regeneron, Glenmark, Galderma, Asana Biosciences, Innovaderm, Dermira, LEO Pharma, Novan, Kyowa Kirin, Concert, Union Therapeutics, and Ralexar; and is consultant for Sanofi, Regeneron, Celgene, Dermira, Galderma, Glenmark, Novartis, Pfizer, LEO Pharma, AbbVie, Eli Lilly, Kyowa Kirin, Mitsubishi Tanabe, Asana Biosciences, Union Therapeutics, Allergan, Amgen, Concert, DS Biopharma, EMD Serono, Escalier, and Flx Bio. BU is an employee of Mount Sinai and has received research funds (grants paid to the institution) from: Incyte, Rapt Therapeutics, and Pfizer. He is also a consultant for Arcutis Biotherapeutics, Bristol Myers Squibb, Castle Biosciences, Galderma, Fresenius Kabi, Pfizer, Primus Pharmaceuticals, Sanofi, and UCB. The other authors have no conflicts of interest. Funding source: None. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Alexander H, Paller AS, Traidl-Hoffmann C, Beck LA, de Benedetto A, Dhar S, et al. The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group. Br J Dermatol. 2020; 182(6): 1331–1342. https://doi.org/10.1111/bjd.18643 10.1111/bjd.18643 CASPubMedWeb of Science®Google Scholar 2Mannschreck D, Feig J, Selph J, Cohen B. Disseminated bullous impetigo and atopic dermatitis: case series and literature review. Pediatr Dermatol. 2020; 37(1): 103–108. https://doi.org/10.1111/pde.14032 10.1111/pde.14032 PubMedWeb of Science®Google Scholar 3Hemani G, Zheng J, Elsworth B, Wade KH, Haberland V, Baird D, et al. The MR-Base platform supports systematic causal inference across the human phenome. elife. 2018; 7:e34408. https://doi.org/10.7554/eLife.34408 10.7554/eLife.34408 PubMedWeb of Science®Google Scholar 4Verbanck M, Chen C-Y, Neale B, Do R. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018; 50: 693–698. https://doi.org/10.1038/s41588-018-0099-7, https://www.nature.com/articles/s41588-018-0099-7 10.1038/s41588-018-0099-7 CASPubMedWeb of Science®Google Scholar 5Kurki MI, Karjalainen J, Palta P, Sipilä TP, Kristiansson K, Donner KM, et al. FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023; 613(7944): 508–518. https://doi.org/10.1038/s41586-022-05473-8 10.1038/s41586-022-05473-8 CASPubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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