Maternal and perinatal outcome of women with early‐onset severe pre‐eclampsia before 28 weeks: Is expectant management beneficial in a low‐resource country? A prospective observational study

医学 赫尔普综合征 子痫 产科 怀孕 队列研究 前瞻性队列研究 外科 内科学 遗传学 生物
作者
Lekha Gangadhar,Sasirekha Rengaraj,Sutharsika Thiyagalingam,B. Adhisivam
出处
期刊:International journal of gynaecology and obstetrics [Wiley]
卷期号:161 (3): 1075-1082 被引量:2
标识
DOI:10.1002/ijgo.14642
摘要

To study the maternal and perinatal outcomes in women with severe pre-eclampsia before 28 weeks of pregnancy.A descriptive study from a tertiary care center. All consecutive women with severe pre-eclampsia withonset before 28 weeks of pregnancy were included. The details were collected in a predesigned structured proforma prospectively.The study cohort included 145 women with a mean maternal age of 26.97 ± 5.36 years (range 19-47 years). The mean duration of prolongation of pregnancy was 13.04 ± 10.57 days (range 1-51 days). A total of 29.7% (n = 43) of women had at least one major adverse maternal outcome, and the most common was HELLP (hemolysis, elevated liver enzymes, low platelet count) syndrome (n = 24,16.6%), followed by eclampsia (n = 12,8.3%). The stillbirth rate was high (n = 103,68.7%), and most occurred in the antepartum period. Of 47 (31.3%) neonates born alive, only eight (17.02%;8/47) survived up to 28 days of life. Fetal growth restriction with Doppler abnormalities and neonatal sepsis were the most common reasons for perinatal mortality.Expectant management should not be considered routinely when the onset of severe pre-eclampsia is before 25+6 weeks of pregnancy. Between 26 and 27+6 weeks it can be offered under close monitoring and the perinatal survival depends on the neonatal services available in their facility.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
wanci应助小幸运采纳,获得10
刚刚
刚刚
111给111的求助进行了留言
刚刚
刚刚
丘比特应助科研里的呆花采纳,获得10
1秒前
领导范儿应助WJ1989采纳,获得200
1秒前
繁荣的鑫发布了新的文献求助10
2秒前
2秒前
空域完成签到,获得积分10
2秒前
wanci应助YXH采纳,获得10
2秒前
3秒前
3秒前
爆米花应助ZZZ采纳,获得10
3秒前
研友_nVq2VL发布了新的文献求助10
4秒前
谦让的绯发布了新的文献求助10
6秒前
英姑应助典雅雁梅采纳,获得10
6秒前
111发布了新的文献求助10
6秒前
个性的大地完成签到,获得积分10
7秒前
852应助健康的幻珊采纳,获得10
7秒前
xy发布了新的文献求助10
8秒前
8秒前
sammi米完成签到,获得积分10
9秒前
seven发布了新的文献求助10
9秒前
9秒前
18062677029完成签到 ,获得积分10
10秒前
10秒前
所所应助小董继续努力采纳,获得10
11秒前
yoyo233完成签到,获得积分10
12秒前
传奇3应助千里独行侠采纳,获得10
12秒前
whooer完成签到,获得积分10
12秒前
搜集达人应助端庄的如花采纳,获得10
12秒前
李健应助11采纳,获得10
13秒前
13秒前
13秒前
15秒前
hlh发布了新的文献求助10
16秒前
勤恳书包完成签到,获得积分10
16秒前
完美世界应助羊冰安采纳,获得10
16秒前
研友_nVq2VL关注了科研通微信公众号
17秒前
潇洒映冬完成签到,获得积分20
17秒前
高分求助中
Shape Determination of Large Sedimental Rock Fragments 2000
Sustainability in Tides Chemistry 2000
Wirkstoffdesign 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
A Dissection Guide & Atlas to the Rabbit 600
Very-high-order BVD Schemes Using β-variable THINC Method 568
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3129128
求助须知:如何正确求助?哪些是违规求助? 2779966
关于积分的说明 7745466
捐赠科研通 2435144
什么是DOI,文献DOI怎么找? 1293924
科研通“疑难数据库(出版商)”最低求助积分说明 623474
版权声明 600542