From NAFLD to MASLD: Promise and pitfalls of a new definition

As members of the nomenclature steering committee, we recognize the significant effort involved by all stakeholders in the procedures leading to the proposal of a nomenclature change from non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction-associated steatotic liver disease (MASLD). The new name could potentially remove stigma, which has been highlighted by patient representatives, and bring awareness to the critical role of insulin resistance in the pathophysiology of “metabolic dysfunction” and liver disease.