已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Positive association between different triglyceride glucose index-related indicators and psoriasis: evidence from NHANES

医学 全国健康与营养检查调查 腰围 甘油三酯 体质指数 优势比 银屑病 内科学 逻辑回归 环境卫生 胆固醇 人口 皮肤病科
作者
Dawei Huang,Rui Ma,Xiaoyuan Zhong,Yuxiong Jiang,Jiajing Lu,Ying Li,Yuling Shi
出处
期刊:Frontiers in Immunology [Frontiers Media]
卷期号:14 被引量:15
标识
DOI:10.3389/fimmu.2023.1325557
摘要

Background Psoriasis is a chronic inflammatory skin disease with effects that extend beyond the skin. Insulin resistance (IR) has been associated with psoriasis, but it remains unclear how indicators related to the triglyceride glucose (TyG) index, which were associate with IR, are associated with the condition. Objective The purpose of this study was to investigate the association between psoriasis and three TyG-related indicators: triglyceride glucose-body mass index (TyG-BMI), triglyceride glucose-waist to height ratio (TyG-WHtR), and triglyceride glucose-waist circumference (TyG-WC). Methods Data from adults aged 20 to 80 years in the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2006 and 2009 to 2014 were utilized. Institutional Review Board approval and documented written consent was obtained from participants by NHANES (Protocol #2005–06). The patients were divided into three groups based on TyG-BMI, TyG-WC, and TyG-WHtR: Q1 (1st quintile), Q2 (2nd-3rd quintiles), and Q3 (4th-5th quintiles). Differences between the groups were further explored. Multivariate logistic regressions were used to investigate the correlation between these three indicators and psoriasis, with results expressed as odds ratios (OR) and 95% confidence intervals (CI). Subgroup analysis and supplementary analysis was further conducted to explore potential influencing factors. Results The study included 9,291 participants, of which 260 had psoriasis. Compared Q2 and Q3 of TyG-BMI, TyG-WC, and TyG-WHtR to Q1, there were significantly associate with psoriasis. Among the three indicators, TyG-WC consistently had the highest OR values in Models 1 and 2 (Model 1: Q3 OR (95% CI) = 2.155 (1.442-3.220); Model 2: Q3 OR (95% CI) = 2.029 (1.341-3.069)). While in Model 3, the TyG-BMI shows more significant relationship with psoriasis (Model 3 of TyG-BMI: Q3 OR (95% CI) = 1.948 (1.300-3.000)). Similar results were observed in the majority of subgroups and in supplementary analysis. Conclusion This study identified a stable and strong positive association between TyG-related indicators (TyG-BMI, TyG-WC, and TyG-WHtR) and psoriasis. This association persisted even after adjusting for multiple factors. It is suggested that high IR is significantly associated with psoriasis.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
希望天下0贩的0应助sigrid采纳,获得10
2秒前
完美世界应助淡定的半梦采纳,获得10
5秒前
ding应助很好采纳,获得10
5秒前
bing发布了新的文献求助10
6秒前
8秒前
弧光完成签到 ,获得积分0
8秒前
bing完成签到,获得积分10
10秒前
HLZ发布了新的文献求助10
12秒前
lmk完成签到 ,获得积分10
15秒前
22秒前
踏实的碧空完成签到 ,获得积分10
22秒前
压缩完成签到 ,获得积分10
25秒前
很好发布了新的文献求助10
27秒前
缓慢的灵枫完成签到 ,获得积分10
29秒前
31秒前
33秒前
NexusExplorer应助Milesgao采纳,获得10
35秒前
lanze发布了新的文献求助10
37秒前
水若琳发布了新的文献求助10
38秒前
早睡早起身体好完成签到,获得积分10
38秒前
白杨木影子被拉长完成签到,获得积分10
40秒前
YYYCCCCC完成签到,获得积分10
41秒前
眼睛大的薯片完成签到 ,获得积分10
42秒前
lunar完成签到 ,获得积分10
52秒前
高大的蜡烛完成签到,获得积分10
57秒前
芜湖起飞完成签到 ,获得积分10
1分钟前
肃肃其羽完成签到 ,获得积分10
1分钟前
山城小肘子完成签到,获得积分10
1分钟前
陈尹蓝完成签到 ,获得积分10
1分钟前
淡定的半梦完成签到,获得积分10
1分钟前
HLZ完成签到,获得积分20
1分钟前
哈哈环完成签到 ,获得积分10
1分钟前
阿亞完成签到,获得积分10
1分钟前
yunjian1583完成签到,获得积分10
1分钟前
多多完成签到,获得积分10
1分钟前
redamancy完成签到 ,获得积分10
1分钟前
Vaseegara完成签到 ,获得积分10
1分钟前
旷野发布了新的文献求助10
1分钟前
上官若男应助科研通管家采纳,获得10
1分钟前
田様应助科研通管家采纳,获得10
1分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
Aktuelle Entwicklungen in der linguistischen Forschung 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989989
求助须知:如何正确求助?哪些是违规求助? 3532034
关于积分的说明 11256053
捐赠科研通 3270900
什么是DOI,文献DOI怎么找? 1805105
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809216