小胶质细胞
神经炎症
生药学
NFKB1型
生物
红豆杉
医学
植物
传统医学
药理学
化学
生物活性
生物化学
炎症
基因
体外
免疫学
转录因子
作者
Meimei Chen,Zhang Fei,Wen Xu,Huangwei Lei,Hong Zhenqiang,Yu Rongjun,Qiang Zhao,Qiuyang Li,Xiaozhen Liu,Yuan Yang,Zhaoyang Yang,Candong Li
标识
DOI:10.1016/j.jep.2024.118943
摘要
As one of the important by-products of Taxus chinensis (Pilg.) Rehder, its fruit (TCF) has a sweet taste, which is commonly used in folklore to make health care wine reputed for enhancing immune function and promoting anti-aging effects, especially popular in the longevity villages of China for a long history. Evidences had showed that Taxus chinensis fruit contained polysaccharides, flavonoids, amino acids and terpenoids, which all were free of toxic compounds , but its medicinal value has not been fully recognized. Our previous studies have found that TCF extract may reverse many biological events, including oxidative stress, inflammatory response, neuronal apoptosis, etc. by in silico methods, suggesting potential avenues for future pharmaceutical exploration in aging and age-related diseases.
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