自噬
PI3K/AKT/mTOR通路
蛋白激酶B
RPTOR公司
细胞生长
癌症研究
细胞生物学
信号转导
肺癌
化学
细胞凋亡
生物
医学
肿瘤科
生物化学
作者
Xiaoqin Luo,Li Wang,R F Wang,Jihong Lian,Mengnan Guo,Hongrui Zhou,Mengxue Zhang,Zhe Yang,Xiaolong Li,Xianran He,Xiuli Bi
出处
期刊:RSC medicinal chemistry
[The Royal Society of Chemistry]
日期:2024-01-01
摘要
Non-small-cell lung cancer (NSCLC), which accounts for approximately eighty-five percent of lung cancer diagnoses worldwide, is a malignancy with high incidence and mortality rates. Among the various antitumor compounds, organic selenium-containing compounds have emerged as a promising class of therapeutic agents for cancer treatment. In the present study, SLL-1A-16, a new organoselenium small molecule, was discovered to exhibit antiproliferative activity against NSCLC both
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