Assessment of four screening tools and retrieval of key questions to detect undiagnosed psoriatic arthritis in Chinese patients with psoriasis: A multicenter study

银屑病性关节炎 医学 银屑病 接收机工作特性 内科学 痹症科 曲线下面积 列线图 逻辑回归 皮肤病科
作者
Ran Cui,Miao Chen,Xia Li,Qian Wang,Qiang Tong,Hua Zhang,Zhiyong Chen,Yi‐Li Tao,Xinling Bi,Hui Deng,Yuan Ding-fen,Dongyi He,Yang‐Feng Ding,Sheng‐Ming Dai
出处
期刊:Journal of Dermatology [Wiley]
卷期号:49 (6): 615-623 被引量:3
标识
DOI:10.1111/1346-8138.16355
摘要

Abstract Several screening tools have been developed to facilitate early diagnosis of psoriatic arthritis (PsA); however, their performance varied greatly across different studies. In this study, we validated and compared the performance of four screening tools in detecting undiagnosed PsA Chinese patients with psoriasis, and determined the key questions and their weights. The four screening tools were the Early Arthritis for Psoriatic Patients (EARP) questionnaire, Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire, Psoriasis and Arthritis Screening Questionnaire (PASQ), and Psoriasis Epidemiology Screening Tool (PEST). The receiver–operator curve (ROC) with area under curve (AUC) was used to determine sensitivity, specificity, and accuracy. Least absolute shrinkage and selection operator and logistic regression were utilized to retrieve key questions, and a nomogram was utilized to visualize their weights. Of 482 psoriasis patients from dermatology clinics, 77 were newly diagnosed with PsA. Another 68 patients with newly diagnosed PsA from rheumatology clinics were incorporated in the analysis. ROC analysis indicated that the optimal cut‐off values for EARP, PASE, PASQ, and PEST were 3, 40, 7, and 3, with corresponding sensitivities of 91.4%, 88.6%, 86.2%, and 88.5%, and specificities of 88.6%, 75.2%, 80.2%, and 83.6%, respectively. The AUC of EARP (0.925) was higher than those of PASE (0.885), PASQ (0.905), and PEST (0.827). However, none of them were sufficiently sensitive to identify pure axial PsA (sensitivities of EARP, PASQ, and PASE were 25.0%, 36.8%, and 42.1%, respectively). Twelve key questions were retrieved from these four tools to establish a nomogram with a high discrimination (C‐index = 0.993) and a good calibration (mean absolute error = 0.014). In conclusion, to screen undiagnosed PsA, EARP has slightly better balanced sensitivity and specificity, and higher accuracy. The retrieval of key questions and nomogram signify the necessity of attributing different scores to differently weighted questions when developing a new screening tool to make it function more efficiently.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
情怀应助优雅采纳,获得10
刚刚
www发布了新的文献求助10
刚刚
17self完成签到,获得积分10
刚刚
RUSH发布了新的文献求助10
1秒前
大成发布了新的文献求助10
1秒前
SciGPT应助好名字采纳,获得10
2秒前
王斌发布了新的文献求助10
2秒前
2秒前
2秒前
许锦程完成签到,获得积分10
3秒前
赘婿应助科研通管家采纳,获得10
3秒前
3秒前
干饭大王应助科研通管家采纳,获得10
3秒前
Lucas应助科研通管家采纳,获得10
3秒前
3秒前
NexusExplorer应助科研通管家采纳,获得10
3秒前
NexusExplorer应助科研通管家采纳,获得10
3秒前
桐桐应助艾小晗采纳,获得20
3秒前
隐形曼青应助科研通管家采纳,获得10
3秒前
4秒前
隐形曼青应助科研通管家采纳,获得10
4秒前
ll应助科研通管家采纳,获得10
4秒前
赘婿应助科研通管家采纳,获得10
4秒前
Longlong应助科研通管家采纳,获得20
4秒前
星辰大海应助科研通管家采纳,获得10
4秒前
今后应助科研通管家采纳,获得10
4秒前
隐形曼青应助科研通管家采纳,获得10
4秒前
4秒前
4秒前
赘婿应助大饼卷肉采纳,获得10
5秒前
5秒前
御风完成签到,获得积分10
6秒前
1351567822应助超爱香菜采纳,获得10
6秒前
灵剑山完成签到,获得积分10
6秒前
阿欣完成签到,获得积分10
6秒前
白紫寒完成签到,获得积分10
6秒前
冷先森EPC发布了新的文献求助10
6秒前
周末万岁发布了新的文献求助10
6秒前
MoPunk发布了新的文献求助10
6秒前
111完成签到,获得积分10
7秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3970240
求助须知:如何正确求助?哪些是违规求助? 3514997
关于积分的说明 11176725
捐赠科研通 3250268
什么是DOI,文献DOI怎么找? 1795244
邀请新用户注册赠送积分活动 875725
科研通“疑难数据库(出版商)”最低求助积分说明 805004