The regioselective annulation of N-methylpyridinium ylides with alkenes enabled by palladium catalysis: access to 3-unsubstituted indolizine derivatives

The first catalytic protocol for the regioselective [3 + 2] annulation of N -methyl pyridinium ylides with alkenes to establish various valuable 3-unsubstituted indolizine derivatives is accomplished via palladium catalysis at the unactivated position.