Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Case Report

CD99 医学 转移 子宫切除术 钙黄绿素 阴道出血 免疫组织化学 病理 内科学 怀孕 波形蛋白 癌症 生物 遗传学
作者
Mami Shibahara,Tomoko Kurita,Midori Murakami,Hiroshi Hano,Yojiro Tsuda,Masanori Hisaoka,Seiji KAGAMI,Yusuke MATSUURA,Kiyoshi Yoshino
出处
期刊:Journal of UOEH [The University of Occupational and Environmental Health, Japan]
卷期号:44 (2): 161-166 被引量:8
标识
DOI:10.7888/juoeh.44.161
摘要

Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are extremely rare, occurring in less than 1% of uterine stromal tumors, and they are considered to have a low malignant potential. Due to the small number of cases, no standard treatment has been defined. A 77-year-old woman with postmenopausal bleeding was admitted to our department. Imaging studies revealed a substantial mass around 30 mm in size on the anterior uterine wall. A total hysterectomy and bilateral salpingo-oophorectomy were performed for further diagnosis and treatment. The tumor revealed histopathological findings of a sex cord-like growth pattern in the form of fascicles, cords, or small nests. Immunohistochemical findings revealed that the tumor cells were positively reactive to alpha-SMA, calretinin, CD99, estrogen receptor, and progesterone receptor, collectively diagnosed as UTROSCT. No recurrence was observed over 12 months after treatment. We experienced the treatment of UTROSCT, an extremely rare tumor that occurs in elderly women. Although most cases of UTROSCT have a benign clinical course, several cases of recurrence and metastasis have been reported. It should be followed up for a long term after treatment.

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