医学
真皮
银屑病
皮肤病科
毛囊
黑色素瘤
病理
皮脂腺
汗水
表皮(动物学)
人体皮肤
汗腺
疾病
解剖
内科学
生物
遗传学
癌症研究
作者
Joey E. Lai‐Cheong,John A. McGrath
出处
期刊:Medicine
[Elsevier]
日期:2009-05-01
卷期号:37 (5): 223-226
被引量:56
标识
DOI:10.1016/j.mpmed.2009.03.002
摘要
Abstract
The skin is the largest organ of the human body. It is a complex epithelial and mesenchymal tissue comprising a multilayered stratified epidermis, adnexal structures such as hair follicles, sweat glands and sebaceous glands, a dermis containing collagen and elastic fibres, and underlying subcutaneous fat. More than 1000 disease entities involving the skin have been described and up to 20% of all patient referrals to general practitioners involve skin pathology. Diseases such as psoriasis, eczema, urticaria and melanoma impose a considerable burden on healthcare resources and impact significantly on patients' quality of life. Knowledge of the structure and function of the skin and its appendages is therefore paramount to understanding the biology of healthy skin and the pathophysiology of skin diseases.
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