Microstructure of transglutaminase-induced gelatin-natamycin fungistatic composite films

In this study, the biodegradable and biocompatible gelatin-based film containing natamycin was crosslinked by transglutaminase (TGase). The profiles of micro structure, secondary structure, physical properties, and antifungal activities were evaluated. The results of electron microscope and Fourier transform infrared spectroscopy (FTIR) indicated that the structures of films were significantly changed. In addition, the environment for microbial growth and the mechanical properties were evaluated with different concentrations of TGase. Moreover, the films could inhibit the growth of fungus based on microbiological assays. The findings in this paper would facilitate the production of gelatin-based fungistatic composite films.