活检
医学
前列腺癌
弹性成像
放射科
癌症检测
经直肠超声检查
前列腺
前列腺活检
超声波
癌症
内科学
作者
Mo Zhang,Peng Wang,Bo Yin,Xiang Fei,Xuewen Xu,Song Yong-sheng
出处
期刊:PubMed
日期:2015-07-01
卷期号:21 (7): 610-4
被引量:12
摘要
To evaluate the application of shear wave elastography (SWE) combined with transition zone biopsy in the detection of prostate cancer (PCa).A total of 489 patients with suspected PCa underwent transrectal ultrasonography (TRUS) and SWE-guided prostatic biopsy. We evaluated the role of SWE combined with transition zone biopsy in promoting the detection rate in comparison with the results of biopsy pathology.The pathological results confirmed 221 malignant and 268 benign cases. Based on systematic biopsy, SWE combined with transition zone biopsy achieved a detection rate of 45. 19% , significantly higher than that of systematic biopsy alone (33.13%) (P < 0.05). The diagnostic sensitivity, specificity, and accuracy of SWE were significantly better than those of TRUS (P < 0.05). The mean elasticity (Emean) of SWE was remarkably higher for malignant than for benign lesions ([40.1 ± 9.5] vs [21.6 ± 8.3] kPa, P < 0.05). With 28.5 kPa as the threshold of the Emean value, the area under the ROC curve was 0. 899, and the diagnostic sensitivity and specificity were 88.71% and 86.23%, respectively.SWE combined with transition zone biopsy could significantly improve the detection rate of prostate cancer.
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