传统医学
汤剂
吹笛者
胃酸
分泌物
阿司匹林
蓼
胃蛋白酶
胃液
牛蒡
生姜
药理学
化学
医学
生物化学
酶
作者
Aruna Agrawal,C.V. Narasimha Rao,K Sairam,V. K. Joshi,Rajesh Kumar Goel
出处
期刊:PubMed
日期:2000-10-01
卷期号:38 (10): 994-8
被引量:48
摘要
Use of Dipaniya Mahakasaya, a group consisting of 10 herbal drugs, has been suggested in Charaka Samhita to improve digestion. Out of these 10 plants, three, viz. P. longum (water decoction), Z. officianalis (water decoction) and Ferula species (colloidal solution) were studied for their antiulcer and mechanism of antiulcer effects in rats. All the drugs in the dose of 50 mg/kg, p.o., 60 min prior to experiment, showed significant protection against gastric ulcers induced by 2 hr cold restraint stress, aspirin (200 mg/kg, 4 hr) and 4 hr pylorus ligation. The antiulcerogenic effect seemed to be due to the augmentation of mucin secretion and decreased cell shedding rather than offensive acid and pepsin secretion which however, were found to be increased by them.
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