谵妄
医学
萧条(经济学)
痴呆
慢度
虚弱综合征
制度化
脆弱性(计算)
弱点
老年学
重症监护医学
精神科
疾病
内科学
虚弱指数
物理
计算机安全
量子力学
计算机科学
经济
宏观经济学
解剖
作者
János Kálmán,Magdolna Pákáski,János Kálmán
出处
期刊:Orvosi Hetilap
[Akademiai Kiado Zrt.]
日期:2014-12-01
卷期号:155 (49): 1935-1951
标识
DOI:10.1556/oh.2014.30039
摘要
Frailty syndrome is defined as extreme stress vulnerability and decreased potential to adapt. The elderly and chronically ill patients are affected mostly. This condition increases the risk of adverse health outcomes as infections, falls, delirium, institutionalization, progression of comorbidities and mortality. The pathophysiological mechanism is a complex immune and neuroendocrine dysregulation. According to the phenotype model, frailty presents when three of the followings occur: weakness, exhaustion, slowness, weight loss and decreased activity, while cumulative model counts the number of health deficits. Aging, frailty, dementia and depression are independent clinical entities; they may present separately but may also potentiate each other. Hence most of the frailty scales assess the physical, mental and social dimensions as well. Mild or moderate frailty is potentially reversible with an individualised caring plan. Given short, easy-to-use screening tools, risk groups can be identified in the primary care and referred to a specialised team for further treatment. Here the authors summarise the literature of a re-discovered, current clinical phenomena, frailty syndrome, focusing on the practical issues in primary care. Orv. Hetil., 2014, 155(49), 1935–1951.
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